Naturally, a decrease in ACTH results in a decrease in the production of cortisol by the adrenal glands. Secondary adrenal insufficiency develops when there is a decrease in the hormone ACTH (Adreno-Cortico-Tropic- Hormone) from the pituitary gland in the brain.ĪCTH regulates the production of cortisol by the adrenal gland. Therefore, these patients have a very low level of cortisol as well as aldosterone.

In this disease, there is a near- total destruction of both of the adrenal glands. Primary adrenal insufficiency is also known as Addison’s disease. What are adrenal glands? Two small triangular structures lying on top of the kidneys.

Actual Case Study of Adrenal InsufficiencyĪdrenal insufficiency occurs when there is a significant decrease in the production of hormone cortisol by the adrenal glands.

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